abstract：BACKGROUND AND AIM:This study aims to evaluate and compare the survival and other portal hypertension-related complications of patients with portal pressure gradient (PPG) ≥ 25 mmHg using transjugular intrahepatic portosystemic shunt (TIPS) as the first-line and second-line therapies in secondary prophylaxis of varicea...

journal_title：Journal of gastroenterology and hepatology

authors： Liu J,Shi Q,Xiao S,Zhou C,Zhou B,Yuan F,Zheng C,Lin S,Qian K,Feng G,Xiong B

更新日期：2020-02-01 00:00:00

abstract：BACKGROUND AND AIM:Bacterial infections are among the main causes of death in patients with cirrhosis. While there are unquestionable benefits of using albumin in patients with spontaneous bacterial peritonitis, the benefits of albumin are controversial for those with extraperitoneal infections. The aim was to compare ...

journal_title：Journal of gastroenterology and hepatology

authors： Leão GS,John Neto G,Jotz RF,Mattos AA,Mattos ÂZ

更新日期：2019-12-01 00:00:00

abstract：BACKGROUND AND AIM:An endoscopic clip device was newly designed to accomplish the closure of large gastrointestinal defects. The aim of this study was to determine the feasibility and efficacy of this device in an ex vivo experimental setting. METHODS:This prospective study was conducted in porcine colons (n = 5). A l...

journal_title：Journal of gastroenterology and hepatology

authors： Wang ZJ,Li SY,Zhang YH,Chen Y,Zhang PP,Li ZS,Bai Y,Wang D

更新日期：2019-12-01 00:00:00

abstract：BACKGROUND AND AIM:We previously discovered that tumor suppressor candidate 3 (TUSC3) was overexpressed and predicted worse prognosis in colon cancer patients. However, the mechanisms of upregulation of TUSC3 in colon cancer remained unclear. METHODS:MiR-873-5p was predicted and identified as the regulator of TUSC3 vi...

journal_title：Journal of gastroenterology and hepatology

authors： Zhu Y,Zhang X,Qi M,Zhang Y,Ding F

更新日期：2019-12-01 00:00:00

abstract：BACKGROUND AND AIM:One of the main concerns related to peroral endoscopic myotomy (POEM) is postoperative gastroesophageal reflux (GER). The two penetrating vessels (TPVs) that are found at the boundary between the circular and oblique muscles in the posterior cardia wall have been suggested to be a good indicator of t...

journal_title：Journal of gastroenterology and hepatology

authors： Tanaka S,Toyonaga T,Kawara F,Watanabe D,Hoshi N,Abe H,Ariyoshi R,Ohara Y,Takao T,Morita Y,Umegaki E,Kodama Y

更新日期：2019-12-01 00:00:00

abstract：BACKGROUND AND AIM:Few studies have evaluated sustained virological response (SVR) rates by direct-acting agents (DAAs) and liver stiffness measurement (LSM) changing post-SVR in limited-resource settings. We aimed to describe the effectiveness of DAAs for hepatitis C virus treatment and to assess the changing of LSM p...

journal_title：Journal of gastroenterology and hepatology

authors： Fernandes FF,Piedade J,Guimaraes L,Nunes EP,Chaves U,Goldenzon RV,Cardoso SW,Duarte J,Grinsztejn B,Veloso VG,Pereira G,Perazzo H

更新日期：2019-12-01 00:00:00

abstract：BACKGROUND:Direct-acting antivirals (DAAs) rapidly clear hepatitis C virus (HCV), but the lipid dynamics after DAA treatment remain unknown. Low-density lipoprotein (LDL) cholesterolemia is the predicting factor for the onset and death of atherosclerotic cardiovascular diseases. Thus, in this study, we examined the fre...

journal_title：Journal of gastroenterology and hepatology

authors： Morihara D,Ko YL,Shibata K,Yamauchi R,Fukuda H,Tsuchiya N,Fukunaga A,Kunimoto H,Iwashita H,Takata K,Tanaka T,Sakurai K,Inomata S,Yokoyama K,Nishizawa S,Takeyama Y,Irie M,Shakado S,Sohda T,Sakisaka S

更新日期：2019-11-01 00:00:00

abstract：BACKGROUND AND AIM:Functional gastrointestinal disorders are the most common disorders in gastroenterology and are currently considered as gut-brain interaction disorders with multiple related factors including motility disturbance. However, high-resolution manometry (HRM) had revealed a new disease concept known as mi...

journal_title：Journal of gastroenterology and hepatology

authors： Sato H,Takahashi K,Mizuno KI,Hashimoto S,Kawata Y,Mizusawa T,Tominaga K,Yokoyama J,Terai S

更新日期：2019-11-01 00:00:00

abstract：BACKGROUND AND AIM:Secreted protein acidic and rich in cysteine (SPARC) is a matricellular glycoprotein that plays a significant role in tumor development. SPARC has been indicated that promotes tumorigenesis, metastasis, and poor prognosis in prostate cancer and lung cancer. Therefore, we sought to investigate the mol...

journal_title：Journal of gastroenterology and hepatology

authors： Jiang X,Liu F,Wang Y,Gao J

更新日期：2019-10-01 00:00:00

abstract：BACKGROUND AND AIM:Tobacco smoking is a risk factor for gastrointestinal disorders, causing mucosal damage and impairing immune responses. However, smoking has been found to be protective against ulcerative colitis (UC). Human leukocyte antigen (HLA) is a major susceptibility locus for UC, and HLA-DRB1*15:02 has the st...

journal_title：Journal of gastroenterology and hepatology

authors： Lee HS,Kim K,Jung S,Hong M,Kim BM,Yoo DS,Moon JW,Baek J,Hwang SW,Park SH,Yang SK,Han B,Song K,Ye BD

更新日期：2019-10-01 00:00:00

abstract：BACKGROUND AND AIM:Renal abnormalities can occur at any time point during the course of Wilson disease (WD). We aimed to fill a literature gap in this respect by studying urinary abnormalities in children and adolescents with WD. METHODS:This study included 60 children with WD presenting to the Pediatric Hepatology Un...

journal_title：Journal of gastroenterology and hepatology

authors： Helmy H,Fahmy M,Abdel Aziz H,Ghobrial C,Abdel Hameed N,El-Karaksy H

更新日期：2019-10-01 00:00:00

abstract：BACKGROUND AND AIM:Incidental pancreatic cystic lesions (PCLs) are being diagnosed more frequently. However, little is known about the prevalence of PCLs in the Chinese population. The aim of the study was to assess the crude prevalence of PCLs in individuals who underwent magnetic resonance imaging (MRI). METHODS:Dat...

journal_title：Journal of gastroenterology and hepatology

authors： Sun L,Wang Y,Jiang F,Qian W,Shao C,Jin Z

更新日期：2019-09-01 00:00:00

abstract：BACKGROUND AND AIM:Although sporadic non-ampullary duodenal adenoma is speculated to be precancerous lesion, the relationship between adenoma and carcinoma remains unclear due to their rarity. Previous studies on sporadic non-ampullary duodenal epithelial neoplasm (SNADEN) have mainly targeted superficial tumors, like ...

journal_title：Journal of gastroenterology and hepatology

authors： Matsueda K,Kanzaki H,Matsueda K,Nasu J,Yoshioka M,Nakagawa M,Inoue M,Inaba T,Imagawa A,Takatani M,Takenaka R,Suzuki S,Tomoda J,Yagi T,Fujiwara T,Tanaka T,Okada H

更新日期：2019-09-01 00:00:00

abstract：BACKGROUND AND AIM:Estimates suggest that in Asia, more than 31 million individuals have hepatitis C virus infection. The present analysis was conducted to assess the efficacy and safety of elbasvir/grazoprevir in Asian participants enrolled in the elbasvir/grazoprevir phase 2/3 clinical trials. METHODS:This is an int...

journal_title：Journal of gastroenterology and hepatology

authors： Wei L,Kumada H,Perumalswami PV,Tanwandee T,Cheng W,Heo J,Cheng PN,Hwang P,Mu SM,Zhao XM,Asante-Appiah E,Caro L,Hanna GJ,Robertson MN,Haber BA,Talwani R

更新日期：2019-09-01 00:00:00

abstract：BACKGROUND AND AIM:Inflammatory bowel disease results from a dysregulated immune response to intestinal microbial flora in individuals with genetic predisposition(s). This study aimed to determine the effects of compound polysaccharides (CP) containing yam polysaccharide and inulin on the rat model of colitis induced b...

journal_title：Journal of gastroenterology and hepatology

authors： Cai Y,Liu W,Lin Y,Zhang S,Zou B,Xiao D,Lin L,Zhong Y,Zheng H,Liao Q,Xie Z

更新日期：2019-09-01 00:00:00

abstract：BACKGROUND AND AIM:Fully covered self-expandable metal stents (FCSEMS) may be better than plastic stents (PS) for preoperative biliary drainage (PBD) to relieve cholangitis or jaundice for resectable malignant biliary obstruction (MBO). However, modification of current FCSEMS designed originally for nonresectable MBO i...

journal_title：Journal of gastroenterology and hepatology

authors： Lee HW,Moon JH,Lee YN,Chung JC,Lee TH,Choi MH,Cha SW,Cho YD,Park SH

更新日期：2019-09-01 00:00:00

abstract：BACKGROUND AND AIM:Population-based studies on post-colonoscopy colorectal cancer (CRC) from Asia are sparse. We aimed to determine the characteristics and predictive factors and survival of post-colonoscopy CRC in Hong Kong. METHODS:This is a territory-wide retrospective cohort study. Patients aged ≥ 40 years with co...

journal_title：Journal of gastroenterology and hepatology

authors： Cheung KS,Chen L,Seto WK,Leung WK

更新日期：2019-09-01 00:00:00

abstract：BACKGROUND AND AIM:Familial adenomatous polyposis (FAP) is the most common adenomatous polyposis syndrome. Patients with FAP are screened for germline mutations of two genes, APC and MUTYH. However, limited data exist on the clinical characterization and genotypic spectrum of FAP in China. This study was aimed to deter...

journal_title：Journal of gastroenterology and hepatology

authors： Li N,Kang Q,Yang L,Zhao XJ,Xue LJ,Wang X,Li AQ,Li CG,Sheng JQ

更新日期：2019-09-01 00:00:00

abstract：BACKGROUND AND AIM:Simultaneous and metachronous head and neck cancers are likely to develop in patients with current or previous esophageal cancer. The Valsalva maneuver facilitates the visualization of the hypopharyngeal area during endoscopic observation, but it requires transnasal endoscopy. We developed a novel Va...

journal_title：Journal of gastroenterology and hepatology

authors： Iwatsubo T,Ishihara R,Nakagawa K,Ohmori M,Iwagami H,Matsuno K,Inoue S,Nakahira H,Matsuura N,Shichijo S,Maekawa A,Kanesaka T,Yamamoto S,Takeuchi Y,Higashino K,Uedo N,Higuchi K

更新日期：2019-08-01 00:00:00

abstract：BACKGROUND AND AIM:In the condition of high prevalence of non-alcoholic fatty liver disease (NAFLD), a new diagnostic algorithm to efficiently identify NAFLD patients with significant fibrosis is urgently required. We evaluated the predictive ability of the fibrosis-4 index (FIB-4 index) for significant liver fibrosis ...

journal_title：Journal of gastroenterology and hepatology

authors： Tomeno W,Imajo K,Kuwada Y,Ogawa Y,Kikuchi M,Honda Y,Kato T,Kessoku T,Kirikoshi H,Yoneda M,Kitahora T,Saito S,Ozawa Y,Nakajima A

更新日期：2019-08-01 00:00:00

abstract：BACKGROUND AND AIM:The goals of the study were to identify an effective treatment for ascites and to examine the influence of tolvaptan on outcomes by investigating non-responders to tolvaptan and comparing outcomes of hepatic cirrhosis in patients treated with and without tolvaptan. METHODS:In Study 1, of 145 patient...

journal_title：Journal of gastroenterology and hepatology

authors： Iwamoto T,Maeda M,Saeki I,Hidaka I,Tajima K,Ishikawa T,Takami T,Sakaida I

更新日期：2019-07-01 00:00:00

abstract：BACKGROUND AND AIM:Barrett's esophagus and colorectal polyps have several overlapping risk factors. Whereas several reports in Western countries have indicated a close relationship between Barrett's esophagus and colorectal polyps, the relationship between these two diseases remains unclear in Japan. This study was per...

journal_title：Journal of gastroenterology and hepatology

authors： Takedomi H,Tsuruoka N,Takamori A,Miyahara K,Yamanouchi K,Shimamura T,Fujimoto Y,Noda T,Matsunaga T,Takara Y,Shimada F,Hidaka H,Endo H,Anzai K,Fujimoto K

更新日期：2019-07-01 00:00:00

abstract：BACKGROUND AND AIM:Chronic inflammation is a major contributor to the initiation and progression of cancers. Lactobacillus helveticus NS8, which was originally separated from fermented koumiss, exhibited anti-inflammatory functions in our prior studies. In this study, NS8 was investigated for its potential to prevent c...

journal_title：Journal of gastroenterology and hepatology

authors： Rong J,Liu S,Hu C,Liu C

更新日期：2019-07-01 00:00:00

abstract：BACKGROUND AND AIM:Physicians use different scales and questionnaires to assess the severity of clinical symptoms in patients with functional gastrointestinal disorders. The current study aimed to validate the "7 × 7" questionnaire for assessment of severity of the symptoms as a tool for the efficacy of treatment of fu...

journal_title：Journal of gastroenterology and hepatology

authors： Ivashkin V,Sheptulin A,Shifrin O,Poluektova E,Pavlov C,Ivashkin K,Drozdova A,Lyashenko O,Korolev A

更新日期：2019-06-01 00:00:00

abstract：BACKGROUND AND AIMS:Patients with cirrhosis and portal hypertension often develop complications relating to hepatic excretory dysfunction. The standard measurement of the hepatic excretion is the constant infusion indocyanine green clearance (ICGCI ) technique. The ICG 15-min retention test (ICG-r15) is faster, more pa...

journal_title：Journal of gastroenterology and hepatology

authors： Møller S,la Cour Sibbesen E,Madsen JL,Bendtsen F

更新日期：2019-06-01 00:00:00

abstract：BACKGROUND AND AIM:Mucosal traction as a "second hand" in endoscopic submucosal dissection (ESD) is very helpful for ESD operators. The efficacy of using a snare combined with endoclips to assist in ESD (SC-ESD) was evaluated whether it could achieve peroral external traction (PET) and peroral internal traction (PIT) a...

journal_title：Journal of gastroenterology and hepatology

authors： Zhang Q,Yao X,Cai JQ,Zhang BH,Wang Z

更新日期：2019-06-01 00:00:00

abstract：BACKGROUND AND AIM:Albumin-bilirubin (ALBI) grade was developed as a new method to assess hepatic function. Sorafenib has been confirmed to be effective in improving survival in patients with advanced hepatocellular carcinoma (HCC). In this study, we investigated the impact of ALBI grade versus Child-Pugh classificatio...

journal_title：Journal of gastroenterology and hepatology

authors： Tada T,Kumada T,Toyoda H,Tsuji K,Hiraoka A,Michitaka K,Deguchi A,Ishikawa T,Imai M,Ochi H,Joko K,Shimada N,Tajiri K,Hirooka M,Koizumi Y,Hiasa Y,Tanaka J

更新日期：2019-06-01 00:00:00

abstract：BACKGROUND AND AIM:Hyponatremia is associated with development of hepatic encephalopathy (HE), but the nature of the relationship between serum sodium and HE incidence is unknown. We examined the association between serum sodium, changes in serum sodium, and HE incidence using data from three randomized trials of satav...

journal_title：Journal of gastroenterology and hepatology

authors： Bossen L,Ginès P,Vilstrup H,Watson H,Jepsen P

更新日期：2019-05-01 00:00:00

abstract：BACKGROUND AND AIM:Opioid-induced constipation (OIC) is a frequent adverse event (AE) that impairs patients' quality of life (QOL). Peripherally acting μ-opioid receptor antagonists (PAMORAs) have been recognized as a treatment option for OIC, but the effect consistent across the studies has not been evaluated. METHOD...

journal_title：Journal of gastroenterology and hepatology

authors： Nishie K,Yamamoto S,Yamaga T,Horigome N,Hanaoka M

更新日期：2019-05-01 00:00:00

abstract：BACKGROUND AND AIM:2 L polyethylene glycol plus an ascorbic acid (PEGA) is known to be as effective. However, 2 L polyethylene glycol-based regimens are often still difficult for patients to tolerate. Therefore, we conducted this study to evaluate the potential of 1 L PEGA with prepackaged low-residue diet (PLD) as an ...

journal_title：Journal of gastroenterology and hepatology

authors： Lee JW,Choi JY,Yoon H,Shin CM,Park YS,Kim N,Lee DH

更新日期：2019-05-01 00:00:00

abstract：BACKGROUND AND AIM:Differentially expressed (DE) genes detected at the population-level through case-control comparison provide no information on the dysregulation frequencies of DE genes in a cancer. In this work, we aimed to identify the genes with universally upregulated or downregulated expressions in colorectal ca...

journal_title：Journal of gastroenterology and hepatology

authors： Song K,Su W,Liu Y,Zhang J,Liang Q,Li N,Guan Q,He J,Bai X,Zhao W,Guo Z

更新日期：2019-05-01 00:00:00

abstract：BACKGROUND AND AIM:Liver stiffness (LS), measured by transient elastography, has been validated as a non-invasive surrogate for liver fibrosis. METHODS:We investigated the long-term predictive ability of LS for hepatocellular carcinoma (HCC) development and overall survival in 1146 patients with chronic hepatitis C by...

journal_title：Journal of gastroenterology and hepatology

authors： Nakagomi R,Tateishi R,Masuzaki R,Soroida Y,Iwai T,Kondo M,Fujiwara N,Sato M,Minami T,Uchino K,Enooku K,Nakagawa H,Asaoka Y,Kondo Y,Tanaka Y,Otsuka M,Kato N,Moriya K,Ikeda H,Koike K

更新日期：2019-05-01 00:00:00

abstract：BACKGROUND AND AIM:Endoscopic transmural drainage has been recognized as the first-line treatment for pancreatic fluid collection (PFC). Currently, three different types of stents have been extensively applied, including double pigtail plastic stent (PS), fully covered self-expanding metal stent (FCSEMS), and novel lum...

journal_title：Journal of gastroenterology and hepatology

authors： Wang Z,Zhao S,Meng Q,Wang S,Chen Y,Wang F,Li Q,Yao J,Du Y,Jin Z,Bai Y,Li Z,Wang D

更新日期：2019-04-01 00:00:00

abstract：BACKGROUND AND AIM:The high-mobility group box 1 (HMGB1) protein plays an important role in a lot of biological behaviors, including DNA damage repair, gene transcription, cell replication, and cell death, and its expression is higher in many solid tumors tissues than in their adjacent normal tissues, and it is always ...

journal_title：Journal of gastroenterology and hepatology

authors： Di X,He G,Chen H,Zhu C,Qin Q,Yan J,Zhang X,Sun X

更新日期：2019-04-01 00:00:00

abstract：BACKGROUND AND AIM:Delayed gastric emptying occurs in more than 50% of chronic diabetic patients, and this is associated with significant impairments in quality of life. Traditional therapy for delayed gastric emptying has focused on supportive treatment, and there is no significant effective therapy. The effect of low...

journal_title：Journal of gastroenterology and hepatology

authors： Wu KL,Chiu YC,Yao CC,Tsai CE,Hu ML,Kuo CM,Tai WC,Chuah SK,Hsiao CC

更新日期：2019-04-01 00:00:00

abstract：BACKGROUND AND AIM:Geographic differences have existed in the management of hepatocellular carcinoma (HCC), and efforts to reduce regional disparities have been initiated. The aim of this study is to use the Nationwide Inpatient Sample to determine if regional disparities in the treatment of HCC continue to exist. MET...

journal_title：Journal of gastroenterology and hepatology

authors： Sobotka LA,Hinton A,Conteh LF

更新日期：2019-03-01 00:00:00

abstract：BACKGROUND AND AIM:The treatment of patients with functional dyspepsia (FD) remains unsatisfactory. We assessed the efficacy of Zhizhu Kuanzhong (ZZKZ) capsule, a traditional Chinese medicine formula, in patients with postprandial distress syndrome (PDS) of FD. METHODS:The study was designed as a multicenter, randomiz...

journal_title：Journal of gastroenterology and hepatology

authors： Xiao Y,Li Y,Shu J,Li Y,Xu J,Ren J,Liu D,Wang J,Zhou L,Li Y,Tang G,Tian D,Zhang S,Hou X,Wang H,Li Z,Lv N,Chen M

更新日期：2019-03-01 00:00:00

abstract：:Gastric varices (GVs) are a major complication of portal hypertension in patients with liver cirrhosis. The mortality rate associated with the bleeding from GVs is not low. Balloon-occluded retrograde transvenous obliteration (BRTO) was first introduced by Kanagawa et al. as a treatment for isolated GVs in 1994. It ha...

journal_title：Journal of gastroenterology and hepatology

authors： Kobayakawa M,Ohnishi S,Suzuki H

更新日期：2019-03-01 00:00:00

abstract：BACKGROUND AND AIM:Results obtained from different hepatitis E virus (HEV) tests are usually inconsistent. The detection of serum HEV antigen (Ag) has been suggested to be more sensitive for the diagnosis of genotypes 1 and 3 HEV. METHODS:We compared the diagnostic accuracies of serum HEV Ag and HEV RNA by using 202 s...

journal_title：Journal of gastroenterology and hepatology

authors： Zhang H,Rao H,Wang Y,Wang J,Kong X,Ji Y,Zhu L,Liu Y,Fang J,Yang M,Luo B,Wang Z,Shi Y,Wang Y,Wang H,Zhao J,Wei L

更新日期：2019-02-01 00:00:00

abstract：BACKGROUND AND AIM:The Baveno VI Consensus recommends repeating examination in patients with high liver stiffness measurement (LSM) by transient elastography to reduce false-positive diagnosis of advanced liver disease. We tested whether repeating transient elastography can increase the overall diagnostic accuracy. ME...

journal_title：Journal of gastroenterology and hepatology

authors： Chow JC,Wong GL,Chan AW,Shu SS,Chan CK,Leung JK,Choi PC,Chim AM,Chan HL,Wong VW

更新日期：2019-01-01 00:00:00